How many chemical structures

How many chemical structures are represented by the Markush structure shown? Question 2 of 7 0.7 From data provided in Bell, et al., which of the following compounds showed the highest selectivity for the IGFRK enzyme over the IRK enzyme? A. 1 B. 2 C. 3 D. 4 E. 5 F. 6 G. 7 Reset Selection Question 3 of 7 0.71 Points From data provided in Bell, et al., which of the following compounds showed the highest potency for the IGFRK enzyme? A. 1 B. 2 C. 3 D. 4 E. 5 F. 6 G. 7 Reset Selection Question 4 of 7 0.71 Points From data provided in Bell, et al., which of the following compounds showed the highest potency for the IRK enzyme? A. 1 B. 2 C. 3 D. 4 E. 5 F. 6 G. 7 Reset Selection Question 5 of 7 0.71 Points The experimental data used to calculate an IC50 are typically which of the following? A. Activity of an enzyme at different enzyme concentrations, in the presence of an inhibitor B. Activity of an enzyme at different time points, in the presence of an inhibitor C. Activity of an enzyme at different substrate concentrations, in the presence of an inhibitor D. Activity of an enzyme at different inhibitor concentrations, in the presence of a substrate Reset Selection Question 6 of 7 0.71 Points In planning a rat PK experiment, how much compound should you have, in order to determine standard PK parameters of a compound. Assume that the rats weigh 200g each, you draw blood at 6 time points, use 5 rats per group, and inject 10mg/kg iv into each rat. A. 1ug B. 10ug C. 100ug D. 1mg E. 10mg F. 100mg Reset Selection Question 7 of 7 0.71 Points A 2g dose of kinetolol was administered to an 80kg healthy volunteer as an iv injection. Plasma concentrations of the drug were measured at various times after the drug administration, and area under the curve (AUC) was calculated to be 200 (mg hour)/L. The total Clearance of the drug is: A. 10 L/hour B. 0.01 hour/L C. 0.01 L/hour D. 10 hour/L

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